Blar i forfatter "Jørgensen, Even Hjalmar"

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    • Arctic charr brain transcriptome strongly affected by summer seasonal growth but only subtly by feed deprivation 

      Striberny, Anja; Jørgensen, Even Hjalmar; Klopp, Christophe; Magnanou, Elodie (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-06-27)
      <i>Background</i>: The Arctic charr (<i>Salvelinus alpinus</i>) has a highly seasonal feeding cycle that comprises long periods of voluntary fasting and a short but intense feeding period during summer. Therefore, the charr represents an interesting species for studying appetite-regulating mechanisms in fish. <p> <p><i>Results</i>: In this study, we compared the brain transcriptomes of fed and ...

    • Diversified regulation of circadian clock gene expression following whole genome duplication 

      West, Alexander Christopher; Iversen, Marianne; Jørgensen, Even Hjalmar; Sandve, Simen Rød; Hazlerigg, David; Wood, Shona Hiedi (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-10-08)
      Across taxa, circadian control of physiology and behavior arises from cell-autonomous oscillations in gene expression, governed by a networks of so-called ‘clock genes’, collectively forming transcription-translation feedback loops. In modern vertebrates, these networks contain multiple copies of clock gene family members, which arose through whole genome duplication (WGD) events during evolutionary ...

    • Immunologic Profiling of the Atlantic Salmon Gill by Single Nuclei Transcriptomics 

      West, Alexander Christopher; Mizoro, Yasutaka; Wood, Shona; Ince, Louise M.; Iversen, Marianne; Jørgensen, Even Hjalmar; Nome, Torfinn; Sandve, Simen Rød; Martin, Samuel A. M.; Loudon, Andrew S. I.; Hazlerigg, David (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-05-04)
      Anadromous salmonids begin life adapted to the freshwater environments of their natal streams before a developmental transition, known as smoltification, transforms them into marine-adapted fish. In the wild, smoltification is a photoperiod-regulated process, involving radical remodeling of gill function to cope with the profound osmotic and immunological challenges of seawater (SW) migration. While ...

    • Impacts of Early Life Stress on the Methylome and Transcriptome of Atlantic Salmon 

      Moghadam, Hooman; Johnsen, Hanne; Robinson, Nick; Andersen, Øivind; Jørgensen, Even Hjalmar; Johnsen, Helge K.; Bæhr, Vegar J.; Tveiten, Helge (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-07-10)
      Exposure to environmental stressors during early-life stages can change the rate and timing of various developmental processes. Epigenetic marks affecting transcriptional regulation can be altered by such environmental stimuli. To assess how stress might affect the methylome and transcriptome in salmon, fish were treated using cold-shock and air-exposure from the eye-stage until start-feeding. ...

    • Mandibular shape in farmed Arctic foxes (Vulpes lagopus) exposed to persistent organic pollutants 

      Bradley, Madison M.; Perra, Megan; Ahlstrøm, Øystein; Jenssen, Bjørn Munro; Jørgensen, Even Hjalmar; Fuglei, Eva; Muir, Derek C.G.; Sonne, Christian (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-07-26)
      We investigated if dietary exposure to persistent organic pollutants (POPs) affect mandibular asymmetry and periodontal disease in paired male-siblings of Arctic foxes (<i>Vulpes lagopus</i>). During ontogeny, one group of siblings was exposed to the complexed POP mixture in naturally contaminated minke whale (<i>Balaenoptere acutorostarta</i>) blubber (n = 10), while another group was given wet ...

    • Modulation of intestinal growth and differentiation by photoperiod and dietary treatment during smoltification in Atlantic salmon (Salmo salar, L.) 

      Duarte, Vilma; Gaetano, Pasqualina; Striberny, Anja; Hazlerigg, David; Jørgensen, Even Hjalmar; Fuentes, Juan; Campinho, Marco A. (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-12-15)
      Atlantic salmon undergo smoltification, a process that prepares the fish to enter and thrive in seawater (SW). Several physiological changes occur during smolting, especially in osmoregulatory tissues, the gill, the kidney, and the intestine. Here we characterized the effects on intestinal morphogenesis of two different, commonly used smoltification regimes during the end of the freshwater phase, ...

    • NFAT5 genes are part of the osmotic regulatory system in Atlantic salmon (Salmo salar) 

      Lorgan, Marlene; Jørgensen, Even Hjalmar; Jordan, William C.; Martin, Samuel AM; Hazlerigg, David (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-06-18)
      The anadromous Atlantic salmon utilizes both fresh and salt water (FW and SW) habitats during its life cycle. The parr-smolt transformation (PST) is an important developmental transition from a FW adapted juvenile parr to a SW adapted smolt. Physiological changes in osmoregulatory tissues, particularly the gill, are key in maintaining effective ion regulation during PST. Changes are initiated ...

    • Photoperiod and dietary treatment in freshwater modulate the short-term intestinal response to seawater in Atlantic salmon (Salmo salar) 

      Gaetano, Pasqualina; Duarte, Vilma; Striberny, Anja; Hazlerigg, David; Jørgensen, Even Hjalmar; Campinho, Marco A.; Fuentes, Juan (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-02-02)
      Stimulation and timing of smoltification are essential for successful Atlantic salmon (Salmo salar) aquaculture. This study investigated intestinal responses during dietary and photoperiod manipulation in freshwater (FW) and after a subsequent seven days residence in seawater (SW). “Small” and “large” Atlantic salmon parr (~40 g and ~ 130 g respectively) were treated in FW for 12 weeks and ...

    • Photoperiod revisited: is there a critical day length for triggering a complete parr–smolt transformation in Atlantic salmon Salmo salar? 

      Strand, Jo Espen Tau; Hazlerigg, David; Jørgensen, Even Hjalmar (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-07-26)
      The present study investigated whether there is a critical length of photoperiod needed to stimulate a completed parr–smolt transformation (PST) in Atlantic salmon <i>Salmo salar</i>. In two experiments, <i>S. salar</i> parr of the Norwegian aquaculture strain held on continuous light were exposed to a short photoperiod (6 L:18D) followed by exposure to 8 L:16D, 12 L:12D, 16 L:8D, 20 L:4D and 24 ...

    • Photoperiod-dependent developmental reprogramming of the transcriptional response to seawater entry in Atlantic salmon (Salmo salar) 

      Iversen, Marianne; Mulugeta, Teshome Dagne; West, Alexander Christopher; Jørgensen, Even Hjalmar; Martin, Samuel A. M.; Sandve, Simen Rød; Hazlerigg, David (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-03-12)
      The developmental transition of juvenile salmon from a freshwater resident morph (parr) to a seawater (SW) migratory morph (smolt), known as smoltification, entails a reorganization of gill function to cope with the altered water environment. Recently, we used RNAseq to characterize the breadth of transcriptional change which takes place in the gill in the FW phase of smoltification. This highlighted ...

    • RNA profiling identifies novel, photoperiodhistory dependent markers associated with enhanced saltwater performance in juvenile Atlantic salmon 

      Iversen, Marianne; Mulugeta, Teshome Dagne; Blikeng, Børge Gellein; West, Alexander Christopher; Jørgensen, Even Hjalmar; Sandve, Simen Rød; Hazlerigg, David (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-04-08)
      Atlantic salmon migrate to sea following completion of a developmental process known as smolting, which establishes a seawater (SW) tolerant phenotype. Smolting is stimulated by exposure to long photoperiod or continuous light (LL) following a period of exposure to short photoperiod (SP), and this leads to major changes in gill ion exchange and osmoregulatory function. Here, we performed an RNAseq ...

    • Seasonal Differences in Relative Gene Expression of Putative Central Appetite Regulators in Arctic Charr (Salvelinus alpinus) Do Not Reflect Its Annual Feeding Cycle 

      Striberny, Anja; Ravuri, Chandra Sekhar; Jobling, Malcolm; Jørgensen, Even Hjalmar (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-09-30)
      The highly seasonal anadromous Arctic charr (Salvelinus alpinus) was used to investigate the possible involvement of altered gene expression of brain neuropeptides in seasonal appetite regulation. Pro-opiomelanocortin (POMCA1, POMCA2), Cocaine and amphetamine regulated transcript (CART), Agouti related Peptide (AgRP), Neuropeptide Y (NPY) and Melanocortin Receptor 4 (MC4-R) genes were examined. The ...

    • Seaward migrating Atlantic salmon smolts with low levels of gill Na+, K+ -ATPase activity : is sea entry delayed? 

      Strand, Jo Espen Tau; Davidsen, Jan Grimsrud; Jørgensen, Even Hjalmar; Rikardsen, Audun H. (Journal article; Tidsskriftartikkel; Peer reviewed, 2010-11-16)
      Two groups of migrating wild Atlantic salmon (Salmo salar) smolts caught within a 1 week interval in the River Alta, northern Norway, were tagged with acoustic transmitters and measured for gill Na+, K+ -ATPase activity in order to compare their smolt status with timing of sea entry. The first group of smolts had low levels of gill Na+, K+ -ATPase activity and resided in the lower part of the river ...